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Showing posts from January, 2022

metabolic acidosis articles

1)Oral bicarbonate therapy in ckd Dubey,  A.K.;  Sahoo,  J.;  Vairappan,  B.;  Haridasan,  S.;  Parameswaran,  S.;  Priyamvada,  P.S.  Correction  of metabolic  acidosis  improves  muscle  mass  and  renal  function  in  chronic  kidney  disease  stages  3  and  4:  A randomized controlled  trial.  Nephrol.  Dial.  Transplant.  2018,  doi:10.1093/ndt/gfy214.  ABSTRACT Background. Metabolic acidosis (MA) is associated with a loss of muscle mass and faster deterioration of kidney function in patients with chronic kidney disease (CKD). A few singlecentre randomized trials have reported favourable outcomes following correction of MA. Additional good quality evidence on the safety and efficacy of alkali supplementation is required in epidemiologically different patient subsets with CKD.  Methods. A single-cent...