Ascites
A 47 yr old male presented to op with c/o
Abdominal distention since 15 days
B/l pedal edema upto thigh since 15 days,with a slight decrease on lying down
Not a/w dyspnoea,fever, decreased urine output,Malena constipation, haematemesis,easy bruisability,
Not a k/c/o dm2 or htn
K/c/o chronic alcoholic since 20yrs consuming 180ml whiskey /day discontinued for the past 2 months due to unavailability of liquor
Not a smoker
Prov diagnosis as per history: alcohol liver disease?cirrhosis(decompendated)
On general examination:
Icterus+
No signs of clubbing
No spidernaevi,palmar erythema,gynecomastia,leukonychia,
Abdominal examination
Appeared tensly distended with no engorged veins ,umbilicus is flat,no striae
Palpation:organs couldn't be palpable
Shifting dullness +(indicating fluid >1000ml)
Fluid thrill absent
Auscultation: bowel sounds present,no bruits
RS:bae+with coarse rt basal crepts
CVS: jvp appeared raised in 90 degree sitting position,upto bifurcation of carotid.
Heart sounds heard in all areas,
Provisional diagnosis based on examination:
Liver failure due to alcohol intake-h/o alcohol ingestion,ascites
Heart failure-pleural effusion,ascites ,pedal edema, jvp raised
Constrictive pericarditis-hepatojugular reflex -sustained, low voltage complexes on ecg
https://www.ncbi.nlm.nih.gov/books/NBK526097/(input from my colleague)
MELD scoring=16 point
Maddreys discrimination factor=53
(>32 is suggestive of poor prognosis and need for anti inflammatory treatment as per theory that interleukins and tnf alpha mediate tissue destruction)
Diagnostic query?
Usg-showed altered echotexture of the liver and splenomegaly which could not be assessed clinically
Hb=6.8, plt 70,000(h/o bleeding per rectum ? haemorrhoids 20days back)
Stool for occult blood-negative.
Lft interpretation:AST/ALT =Less than one with no fourfold increase in their values as expected
Alb 2.8- suggests chronic pathology as half life of albumin is 21 days , and overload features probably due to hypoalbuminemia.
Which is not -nephrotic syndome/?protein loosing enteropathy - no loss of protein in urine
Expected SAAG- >1.1, with ?ascitic protein evaluation for differentiating cardiac and liver causes
Taught my intern the procedure and the method of evaluation.
Colour- straw,clear.
SAAG-2.5 (high )
Ascitic protein-0.7(suggestive of liver /biliary tract pathology)
With sugar -111, tlc-200, lymphocyte predominance, and cytology negative for malignancy
2d echo- mild TR with mild PAH.
Treatment
Loop diuretics with aldactone
Salt and water restriction
High protein diet
Advice regarding alcohol abstinence....(hopefully will follow up on that)
Abdominal distention since 15 days
B/l pedal edema upto thigh since 15 days,with a slight decrease on lying down
Not a/w dyspnoea,fever, decreased urine output,Malena constipation, haematemesis,easy bruisability,
Not a k/c/o dm2 or htn
K/c/o chronic alcoholic since 20yrs consuming 180ml whiskey /day discontinued for the past 2 months due to unavailability of liquor
Not a smoker
Prov diagnosis as per history: alcohol liver disease?cirrhosis(decompendated)
On general examination:
Icterus+
No signs of clubbing
No spidernaevi,palmar erythema,gynecomastia,leukonychia,
Abdominal examination
Appeared tensly distended with no engorged veins ,umbilicus is flat,no striae
Palpation:organs couldn't be palpable
Shifting dullness +(indicating fluid >1000ml)
Fluid thrill absent
Auscultation: bowel sounds present,no bruits
RS:bae+with coarse rt basal crepts
CVS: jvp appeared raised in 90 degree sitting position,upto bifurcation of carotid.
Heart sounds heard in all areas,
Provisional diagnosis based on examination:
Liver failure due to alcohol intake-h/o alcohol ingestion,ascites
Heart failure-pleural effusion,ascites ,pedal edema, jvp raised
Constrictive pericarditis-hepatojugular reflex -sustained, low voltage complexes on ecg
https://www.ncbi.nlm.nih.gov/books/NBK526097/(input from my colleague)
MELD scoring=16 point
Maddreys discrimination factor=53
(>32 is suggestive of poor prognosis and need for anti inflammatory treatment as per theory that interleukins and tnf alpha mediate tissue destruction)
Diagnostic query?
Usg-showed altered echotexture of the liver and splenomegaly which could not be assessed clinically
Hb=6.8, plt 70,000(h/o bleeding per rectum ? haemorrhoids 20days back)
Stool for occult blood-negative.
Lft interpretation:AST/ALT =Less than one with no fourfold increase in their values as expected
Alb 2.8- suggests chronic pathology as half life of albumin is 21 days , and overload features probably due to hypoalbuminemia.
Which is not -nephrotic syndome/?protein loosing enteropathy - no loss of protein in urine
Expected SAAG- >1.1, with ?ascitic protein evaluation for differentiating cardiac and liver causes
Taught my intern the procedure and the method of evaluation.
Colour- straw,clear.
SAAG-2.5 (high )
Ascitic protein-0.7(suggestive of liver /biliary tract pathology)
With sugar -111, tlc-200, lymphocyte predominance, and cytology negative for malignancy
2d echo- mild TR with mild PAH.
Treatment
Loop diuretics with aldactone
Salt and water restriction
High protein diet
Advice regarding alcohol abstinence....(hopefully will follow up on that)
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